Abboud, N., and A. Casadevall. 2008. Immunogenicity of Bacillus anthracis protective antigen domains and efficacy of elicited antibody responses depend on host genetic background. Clin Vaccine Immunol 15:1115-1123.

Dam TK, Torres M, Brewer CF, Casadevall A. 2008. Isothermal titration calorimetry reveals differential binding thermodynamics of variable region-identical antibodies differing in constant region for a univalent ligand. J Biol Chem; 283:31366-70.

Ivanov MI, Noel BL, Rampersaud R, Mena P, Benach JL, Bliska JB. 2008. Vaccination of mice with a Yop translocon complex elicits antibodies that are protective against infection with F1- Yersinia pestis. Infect Immun 76:5181-90.

Vaccines

Kopecky-Bromberg SA, Fraser KA, Pica N, Carnero E, Moran TM, Franck RW, Tsuji M, Palese P. 2009. Alpha-C-galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine. Vaccine 27:3766-74.

Gao, Q., E. W. Brydon, and P. Palese. 2008. A seven-segmented influenza A virus expressing the influenza C virus glycoprotein HEF. J Virol 82:6419-6426

Rose, N. F., J. Publicover, A. Chattopadhyay, and J. K. Rose. 2008. Hybrid alphavirus-rhabdovirus propagating replicon particles are versatile and potent vaccine vectors. Proc Natl Acad Sci U S A 105:5839-584

Diagnostics and Pathogen Discovery

Solovyov A, Palacios G, Briese T, Lipkin WI, Rabadan R. 2009. C luster analysis of the origins of the new influenza A(H1N1) virus. Euro Surveill ;14.

Palacios, G., J. Druce, L. Du, T. Tran, C. Birch, T. Briese, S. Conlan, P. L. Quan, J. Hui, J. Marshall, J. F. Simons, M. Egholm, C. D. Paddock, W. J. Shieh, C. S. Goldsmith, S. R. Zaki, M. Catton, and W. I. Lipkin. 2008. A new arenavirus in a cluster of fatal transplant-associated diseases. N Engl J Med 358:991-998.

Quan PL, Briese T, Palacios G, Lipkin WI. 2008. Rapid sequence-based diagnosis of viral infection. Antiviral Res 79:1-5.

Therapeutics

Porotto M, Orefice G, Yokoyama CC, Mungall BA, Realubit R, Sganga ML, Aljofan M, Whitt M, Glickman F, Moscona A. 2009. Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy. J Virol 83:5148-55.

Porotto M, Yokoyama CC, Orefice G, Kim HS, Aljofan M, Mungall BA, Moscona A. Kinetic dependence of paramyxovirus entry inhibition. J Virol 2009;83:6947-51.

Porotto M, Carta P, Deng Y, Kellogg GE, Whitt M, Lu M, Mungall BA, Moscona A. 2007. Molecular determinants of antiviral potency of paramyxovirus entry inhibitors. J Virol 81:10567-74.

Innate Immunity

Ciancanelli MJ, Volchkova VA, Shaw ML, Volchkov VE, Basler CF. Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism. J Virol 2009;83:7828-41.

Prins KC, Cardenas WB, Basler CF. Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. J Virol 2009;83:3069-77.

Puig-Basagoiti F, Tilgner M, Bennett CJ, Zhou Y, Munoz-Jordan JL, Garcia-Sastre A, Bernard KA, Shi PY. 2007. A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis. Virology 361:229-41.

Microbial Pathogenesis

Pan X, Luhrmann A, Satoh A, Laskowski-Arce MA, Roy CR. 2008. Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science 320:1651-4.

Runco LM, Myrczek S, Bliska JB, Thanassi DG. 2008. Biogenesis of the fraction 1 capsule and analysis of the ultrastructure of Yersinia pestis. J Bacteriol 190:3381-5.

Grabenstein JP, Fukuto HS, Palmer LE, Bliska JB. 2006. Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages. Infect Immun 74:3727-41.

Developmental Projects

Goldman, D. L., W. Zeng, J. Rivera, A. Nakouzzi, and A. Casadevall. 2008. Human serum contains a protease that protects against cytotoxic activity of Bacillus anthracis lethal toxin in vitro. Clin Vaccine Immunol 15:970-973

Pan, X., A. Luhrmann, A. Satoh, M. A. Laskowski-Arce, and C. R. Roy. 2008. Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science 320:1651-1654

Sudarsan, N., E. R. Lee, Z. Weinberg, R. H. Moy, J. N. Kim, K. H. Link, and R. R. Breaker. 2008. Riboswitches in eubacteria sense the second messenger cyclic di-GMP. Science 321:411-413

New Opportunities

Lu H, England K, am Ende C, Truglio JJ, Luckner S, Reddy BG, Marlenee NL, Knudson SE, Knudson DL, Bowen RA, Kisker C, Slayden RA, Tonge PJ. 2009. Slow-onset inhibition of the FabI enoyl reductase from francisella tularensis: residence time and in vivo activity. ACS Chem Biol 4:221-31.

Pavlova O, Mukhopadhyay J, Sineva E, Ebright RH, Severinov K. 2008. Systematic structure-activity analysis of microcin J25. J Biol Chem 283:25589-95.

Yoder JM, Aslam RU, Mantis NJ. 2007. Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication. Infect Immun 75:1745-50.

Yoder, J. M., R. U. Aslam, and N. J. Mantis. 2007. Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication. Infect Immun 75:1745-1750

Career Development

Moudy RM, Zhang B, Shi PY, Kramer LD. 2009. West Nile virus envelope protein glycosylation is required for efficient viral transmission by Culex vectors. Virology 387:222-8.

Aguilar, P. V., L. W. Leung, E. Wang, S. C. Weaver, and C. F. Basler. 2008. A five-amino-acid deletion of the eastern equine encephalitis virus capsid protein attenuates replication in mammalian systems but not in mosquito cells. J Virol 82:6972-6983.

Jelley-Gibbs, D. M., J. P. Dibble, D. M. Brown, T. M. Strutt, K. K. McKinstry, and S. L. Swain. 2007. Persistent depots of influenza antigen fail to induce a cytotoxic CD8 T cell response. J Immunol 178:7563-7570